

They also represent a key, challenging subfield at the forefront of theoretical and computational chemistry. Proteins, in general, and enzymes, in particular, play key roles in chemical and biological processes.

Quantum-mechanical Thermodynamic Cycle Perturbation.Quantum Mechanics/Molecular Mechanics/Molecular Dynamics.Own N-layer Integrated Molecular Orbital Molecular Mechanics.Local Coupled-Cluster Theory with Single and Double Excitations and Noniterative Perturbative Triples.Conductor-like Polarizable Continuum Model.Email: Search for more papers by this author Email: and Shideh Ahmadi, Department of Chemistry, CMS - Centre for Molecular Simulation, IQST- Institute for Quantum Science and Technology and Quantum Alberta, University of Calgary, 2500 University Drive N.W., Calgary, AB, Canada T2N 1N4. Salahub, Department of Chemistry, CMS - Centre for Molecular Simulation, IQST- Institute for Quantum Science and Technology and Quantum Alberta, University of Calgary, 2500 University Drive N.W., Calgary, AB, Canada T2N 1N4. of Chemistry, CMS - Centre for Molecular Simulation, IQST- Institute for Quantum Science and Technology and Quantum Alberta, University of Calgary, 2500 University Drive N.W., Calgary, AB, Canada, T2N 1N4Ĭollege of Chemistry and Chemical Engineering, Henan University of Technology, No.100, Lian Hua Street, High-Tech Development Zone, Zhengzhou, 450001 People's Republic of China Correspondence Dennis R.An increase in liver enzymes does not necessarily mean damage to the liver. The normal ranges of LFTs vary from laboratory to laboratory. Liver enzymes can also be elevated in liver cancer, hypothyroidism, alcoholic hepatitis, CMV infection, heart diseases, pancreatitis, polymyositis, celiac disease, inflammation of gall bladder, and liver cirrhosis. Other common causes include hepatitis A, hepatitis B, hepatitis C, and obesity. The excess fat in the liver inflames the liver and ultimately leads to cirrhosis of liver. An overweight or fatty liver may also cause liver enzymes to be elevated. The most common causes for elevation of liver enzymes include alcohol abuse, medications such as pain relievers, medications for seizures, antibiotics, and medications to lower cholesterol levels, antidepressant drugs, niacin, and cardiovascular drugs. Increase in PT might indicate liver damage, but it is also elevated with anticoagulant therapy. Normal range of PT is 9.5 to 13.8 seconds. Prothrombin Time (PT): It is the time taken by blood to clot. An increased level of bilirubin in blood indicates jaundice and other liver diseases as well as hemolytic anemia. Normal levels of bilirubin are around 0.1 to 1.2 milligrams per deciliter. It is a waste product that is passed through the liver to be excreted in stools. Decreased albumin or total protein level indicates liver damage/disease.īilirubin: It is a byproduct of normal red blood cell breakdown. The normal range of albumin in blood is 3.5 to 5.0 g/dL and total protein in blood is 6.3 to 7.9 g/dL. It has several functions in the body including binding of water, cations, hormones, fatty acids, bilirubin, T4 and drugs and regulating oncotic pressure of the blood. Albumin and Total Protein: Albumin is a protein that is made by liver and accounts for about 60% of total protein.
